ACHIEVING BEAUTIFUL SKIN

Mesotherapy has been used for over 100 years, and was taken into mainstream medicine in France in 1988. It was developed by Dr Michael Pistor in 1952 for the management of pain and vascular disorders… “little volume, few times and in the right place.”

• Point by point: solution is injected perpendicular to the skin (4mm) and injected about 1-2 cm apart for fat reduction.
• Nappage: superficial injections (2mm) at a 45 degree angle, introducing a drop of fluid at each point.
• Epidermic: very superficial (1mm), light pressure, skin not really penetrated deeply, more of a scratching of the surface.
• Papules: 2-4mm for wrinkles and alopecia.

This is local intradermal therapy with a drug or other substances. They are introduced in tiny amounts through small multiple punctures into the skin, directly into the area in question. The method by which the treatment works is dependent on the mesotherapy mixture used and the original problem. For example, for skin revitalisation, collagen is produced. There are three main challenges treated with Mesotherapy:

• Body: cellulite, dissolving fat
• Skin: rejuvenation, lifting, improved glow
• Hair: telogen effluvium, androgenic alopecia

Meso does not refer to treatment of any condition in particular, it describes a method of drug delivery.

• Various materials! Such as… amino acids (e.g. arginine, cystine, glutamine etc), vitamins (e.g. Vitamin A, C, E etc), minerals (e.g. magnesium, sodium etc), nucleosides (e.g. deoxyadenosine, deoxycytidine etc), co-enzymes (e.g. co enzyme q10, NAD), glutathione, flavonoids, plant extracts, hyaluronic acid. In the case of stimulating collagen production, substances are included which create a favourable environment for this.
• These substances are selected according to the purpose of the mesotherapy. For example, Vitamin C is added because it speeds up DNA synthesis and is essential for collagen synthesis. Vitamin B2 is involved in getting energy from carbohydrates and fat.
• To treat cellulite: l-carnitine, caffeine, isoproterenol, thyroxine (lipolytic), rutin, aminophylline, pentoxiphylline (venostatic), artichoke and gingko biloba (drainage), procaine (anaesthetic), collagenase, hyaluronidase (connective tissue breakdown).
• For skin improvement: hyaluronic acid, multivitamins and trace elements (ionic balance of the skin), amino acids and vegetal proteins (protein reconstruction), dimethylaminoethanol (causes muscle contraction leading to muscle firmness), hexapeptide 3 (relaxes muscles and smooths wrinkles)
• Alopecia: multivitamins, sometimes finasteride and minoxidil

Ionised and neutral drugs can be transported into the dermis and subcutaneous tissue by electroporation, hydrophoresis or other methods. It is mainly used for treating cellulite, reducing wrinkles and skin lifting.

It can be used to deliver anti-inflammatory or analgesic drugs in the treatment of pain. It can also be used for alopecia.

Yes, mesotherapy for the hair is particularly common, as it also is for dark circles around the eyes.

Yes, and it really works best on those who have mild to moderate skin issues.

Unfortunately, no, there is no cream which will tighten or give as much skin improvement as this.

It’s important to note that results with mesotherapy are modest. This treatment is best used for issues that have few other suitable treatments (for example, dark circles), improvement of cellulite, and flaccidity. Treatments for skin rejuvenation for fine lines are better treated with an injectable moisturiser.

First, we decide on the right cocktail for you, dependent on what we’re treating. In the case of anything which is nappage or papular mesotherapy, it’s best to apply some topical anaesthetic 45 minutes prior to the appointment to minimise discomfort – likewise if the hair is to be treated. Any makeup will be removed, and a picture taken of the area we are going to treat. If epidermal mesotherapy is to be used, then a mesotherapy gun is used to introduce the cocktail to the skin with lots of tiny very superficial injections. If other techniques are to be used, then the procedure is generally performed by hand. It is carried out in a stepwise fashion, covering one area of skin at a time. Following the treatment, the skin is cleaned. In the case of mesotherapy for cellulite or flaccidity, the area is cleaned and fewer injections are used for this area. Slightly more fluid is injected per needle insertion point.

It’s helpful if you don’t wear any makeup when you come in for the procedure, in order to reduce the risk of infection – but don’t worry, we can take it off for you. If you’re prone to bruising, you may want to get some arnica or bromelain.

If you’re prone to bruising, you may wish to use arnica or bromelain.

Certain deeper Mesotherapy treatments are more uncomfortable than others, particularly ones requiring multiple punctures on the skin. Sometimes topical anaesthetic is used prior to treatment to minimise any discomfort.

Due to the small pin pricks all over the face, you may not wish to immediately return to work. It might be better to wait a few days, so having the treatment performed on a Friday makes sense, so you have the weekend to recover.

Yes, if you’ve had topical local anaesthetic – but once this has worn off, you’ll quickly feel normal again.

You can wear sterile surgical makeup following your procedure, which we have at the clinic. Please don’t put your regular makeup on until the day after the procedure, to minimise the risk of infection.

It will take a few weeks to see the final effect after the last session of the procedure, because we’re waiting for your body to produce collagen in response to the treatment.

This treatment is not approved for use during pregnancy or whilst breastfeeding.

For any non-surgical procedure, you should be at least 18. We prefer slightly older patients, to ensure you’ve had sufficient time to consider whether this treatment is for you.

There are set treatment protocols which should be adhered to for the best results. In most cases, this will involve one to two sessions per week for a certain number of weeks.

Yes, you’ll be back to normal very quickly after treatment, and in fact even if wrinkle relaxation is carried out, you will still be able to move your face as results are very subtle.

Short term side effects include pain, redness, swelling and bruising. Significant complications are rare.

Nothing, you simply return to your pre-treatment state after a period of time.

No, rejuvenating Mesotherapy is more to improve the texture and tone of the skin rather than filling it out. wrinkle relaxation can be used in a Mesotherapy solution, but the effects are much subtler than would be seen than with a regular wrinkle relaxation treatment

• Cellulite: use in combination with carboxytherapy
• Dark circles: use in combination with PRP and carboxytherapy
• Crêpey skin around the eyes: use in combination with PRP or carboxytherapy
• Generally, crêpey skin: use in combination with injectable moisturisers, carboxytherapy or PRP

Yes, and this is one of the more popular ways of injecting PRP. This can either be done using the epidermic, nappage or papule technique. When using either the nappage or papule technique it may be necessary to use topical anaesthesia beforehand.

All are effective; sometimes it’s better to combine the type of treatment carried out in order to get the best results.

Both these treatments are effective for cellulite improvement, and should probably be combined for the best results. With both, you need to have a number of treatments to get the best results, possibly slightly fewer for mesotherapy.

It’s our preference to do a more traditional injectable moisturiser treatment rather than mesotherapy if possible, as this tends to give a more impactful result.

Please note that you are paying for the treatment only and no guarantee is made of any outcome. Refunds cannot be given under any circumstances, as the product has been used and the service has been delivered.

First reported in France in 1932, it was originally carried out through the skin by application of water-saturated CO2 directly to the skin. It was used for the medical treatment of skin ulcers.

Carbon dioxide gas is administered under the skin. The gas causes an increase in blood flow and skin temperature, and the growth of new capillaries. The stretching during treatment caused by the introduction of the gas causes inflammation which triggers the repair and regeneration response. We see fat breakdown caused by higher temperature and an increase in local blood flow. Cellulite appearance is improved, and the skin looks healthier and tighter. There’s a sharp scratch as the needle is inserted. You can feel the gas quickly rushing beneath the skin (it’s rather uncomfortable due to the stretching). You can feel the gas expanding the tissues and running underneath the skin, in the path of least resistance. The gas is introduced for about 15 seconds. As soon as the needle is taken out, the gas is taken into the blood stream, and any discomfort is minimal after around 90 seconds to two minutes. Sometimes, a second pass is performed which does not have the same sensation due to the analgesic effect of carboxytherapy.

Of course, many men want more toned skin in the abdominal area for example, or to treat dark circles around their eyes.

Yes, and it really works best on those who have mild to moderate skin laxity. Those with severe laxity may need to consider surgery instead.

Unfortunately, no, there is no cream which will tighten or give as much skin improvement as a slightly invasive treatment such as this.

This is a very versatile treatment. The common areas to treat include dark circles around the eyes, fatty tissue in the abdomen, thigh and knee, and cellulite. It’s also good for reducing irregularities after liposuction procedures, as well as facial rejuvenation and stretch marks.

It’s important to note that results with carboxytherapy are modest. This treatment is best used for issues that have few other suitable treatments (for example dark circles), crêpey skin around the eyes, and skin tightening in tough areas such as the neck, or improvement of cellulite.

It’s important that any carboxytherapy treatment is performed after a consultation to make sure it’s right for you. A picture is taken of the area we are going to treat. A very small needle is inserted under the skin, which releases the gas at a steady rate. The gas flows into the tissues and expands them. Typically for the eye region, one to two insertions are required. For other areas, it depends on the size of the area. The area will swell up due to the gas, and in the case of carboxytherapy for the eye, you may not be able to open the eye for a couple of minutes. This is normal, so don’t be alarmed! You’ll see that the gas disperses extremely quickly, as it’s taken up into the blood stream, leaving the treated area feeling a little hot. You’ll be completely back to normal after half an hour or so. It’s better if the appointments are taken close to each other if possible, in order to see results more quickly. However, if there’s a need to space them out more, then this approach is also fine.

It’s helpful if you don’t wear any makeup when you come in for the procedure, in order to reduce the risk of infection – but don’t worry, we can take it off for you. If you’re prone to bruising, you may want to get some arnica or bromelain.

The majority of patients do not bruise. If you’re prone to bruising, you may wish to use arnica or bromelain to help reduce it.

The area is very uncomfortable for about 90 seconds once the gas has been introduced; a strong swelling sensation. This is normal and subsides very quickly. Also, carbon dioxide gas has a mild analgesic effect, meaning that if the same area is treated more than once in the same session, the second pass is much less painful.

It will take a few weeks to see the final effect after the last session of this procedure, because we’re waiting for your body to produce collagen in response to the gas.

Yes, you can return to work immediately afterwards.

Immediately after treatment you can apply a surgical makeup if desired; we have some in the clinic. You can apply regular makeup from the next day.

This treatment is not approved for use during pregnancy or whilst breastfeeding.

Up to ten sessions are required to give the best results. These should be carried out in a short time window, with two to four sessions being carried out per week. Following this, further sessions should be carried out every three to six months to maintain results.

Nothing; the tissues simply age as they did before, although you will have improved tightness over and above what it would have otherwise been.

For any non-surgical procedure, you should be at least 18. We prefer slightly older patients to ensure that you have had sufficient time to consider whether this treatment is for you.

Yes; you’ll be back to normal very quickly after treatment.

Whilst complications are rare, they can and do happen. This can range from a bruise to swelling that lasts a little longer than anticipated, but apart from this, carboxytherapy is virtually risk-free.

No, because nothing is put inside the skin, with the exception of the carbon dioxide gas. This makes it suitable for those who don’t wish to have injectables but would still like to have some skin rejuvenation, utilising their own regenerative process to deliver the results they are after.

Carboxytherapy is an unpredictable treatment because of its reliance on the body’s regenerative factors. As with all treatments such as this, some people respond very well, others averagely and others not at all. Unfortunately, there is no way to predict who will respond well and who will not.

• For cellulite: use in combination with mesotherapy
• Dark circles: use in combination with PRP
• Crêpey skin around the eyes: use in combination with PRP
• Generally, crêpey skin: use in combination with injectable moisturisers or PRP

Both are effective, although PRP may require fewer treatment sessions for the same benefit. You can use carboxytherapy as an adjunct to PRP to supercharge your result.

Carboxytherapy is not as effective at removing small deposits of fat as these other treatments. It is good to smooth any post lipo irregularities in the skin, or to make the skin look healthier after any of these procedures, by increasing the blood flow.

Both of these treatments are effective for cellulite improvement, and can be combined for best results. With both, you need to have a number of treatments to get the best results, possibly slightly fewer for mesotherapy.