The skin is a master at self-renewal, so sometimes all we need to do is to help it along a bit – by using some rather clever technology and your own blood cells.


Platelet rich plasma (PRP) therapy is a leading-edge, natural way to rejuvenate your skin. Using your own blood cells, it harnesses your body’s natural self-renewal function to powerfully treat all kinds of skin issues, such as sun damage, roughness and discolouration.

We’ll take a small amount of your blood and spin it in a centrifuge to harvest your nutrient-rich plasma. We’ll then inject the PRP where it’s most needed to make your complexion glow with renewed youthful luminosity.

PRP is the ideal solution for textural improvement, and it’s also perfect for tackling dark circles or crêpey skin under the eyes.


PRP can help in other areas too like stimulating new hair growth, it’s all about harnessing your body’s own capacity for renewal and regeneration.

Under-eye PRP with Sarah instantly made my
eye bags less crêpey – can’t wait to see what
the recommended three sessions can do!

Ingeborg van Lotringen
Beauty Director, Cosmopolitan

Rejuvenate your skin at The Lovely Clinic

We usually recommend three to five treatments spread out about one month apart, with maintenance top-ups every three to six months. PRP doesn’t generally require social downtime, but treatment under the eyes can result in 12 to 48 hours of swelling.


What is PRP?

PRP stands for platelet rich plasma, and is a preparation of your own platelets in concentrated plasma. It contains various growth factors such as platelet-derived growth factor (PDGF), transforming growth factor (TGF) vascular endothelial growth factor (VEGF) and insulin-like growth factor (IGF). These substances are known to regulate cell repair and regeneration. PRP also contains plasma proteins, fibrin and fibronectin, which act as scaffold for the connective tissue and fresh cell growth.

How long has PRP been used for?

PRP was first developed in the 1970s, and since then has been used in many medical fields – such as dentistry, sports medicine, gastrointestinal surgery, pain management and cosmetic surgery.

Can you tell me about the different types of PRP available?

The quality of PRP produced is dependent on the exact machine used to extract the blood from the PRP machine. Current methods deliver around three to eight times the blood. The blood is taken and centrifuged.

Is this treatment for men?

Yes, many men have PRP; the most common indication is for the hair, or the hair in combination with the eyes.

Why is PRP used?

PRP is generally used to improve the appearance of areas which would otherwise be difficult to treat, such as crêpey tissue around the eyes, or for general skin improvement. Some people use it as a preventative measure, hoping that by stimulating the skin with growth factors, the signs of ageing will not be visible as quickly. It can be used for the O-Shot (though this is not a treatment that we currently offer at TLC) and also for hair growth stimulation. It can also be used after a resurfacing treatment such as microneedling or INTRAcel.

Can PRP be preventative?

PRP is often described as preventative, as the idea is to keep the skin in great working order, so small lines and wrinkles do not form.

Can I just use a cream to get the same result?

You can use stem cell creams which act via cell-signalling mechanisms – however, they’re not human derived, and they’re not from you, so they’re not as powerful, and not exactly the same molecules you require.

Which areas can be treated?

Pretty much anywhere! It works very well in the eye area, and in some cases can help to improve dark circles under the eyes. It’s also good for general skin rejuvenation in the neck, décolletage and hands. In addition, it can be used for the O-Shot in the vagina or penis (though this is not a treatment that we currently offer at TLC) and also to treat hair loss. It can be combined with microneedling for scars and stretch marks.

Can I use PRP on the body?

Sure! PRP is good for the improvement of hair loss, and can also be used for stretch marks and scars when combined with microneedling.

Can it be used for hair?

Yes, and many men use PRP as an adjunct to other hair therapies, such as minoxidil, or leading up to, or following, a hair transplant.

Is there anything it can’t treat?

PRP is not a replacement for lost volume in the skin, so if this is your main concern, PRP will not help.

How does the appointment work?

It’s important that any PRP treatment is performed after a consultation to make sure it’s right for you. If we’re treating the face, a picture will be taken of you in 3D to see any areas of asymmetry. Any makeup is removed. Your blood is taken, just like with a blood test. Do not worry if you don’t have good, visible veins; we have an Accuvein at the clinic which allows us to see the position of veins under the skin, so blood can be taken much more easily. The amount of blood taken depends on which procedure we’re performing. The blood is placed in one of our centrifuges and spun. The time taken to spin depends on which centrifuge is used, and is usually between six and twenty minutes. You can even grab a coffee whilst your blood is spinning.

In the case of mesotherapy, we use a gun to introduce the PRP back to the skin. This causes lots of imperceptible scratches on the face, though there’s usually nothing visible on the face after treatment. With mesotherapy, try not to wash your face until the next day. With the other treatments, it’s fine to wash.

If you’re only having eye rejuvenation, a cannula is used to apply the PRP, and there’s usually swelling after the treatment which can be persistent for up to 48 hours. You may wish to bring sunglasses with you to the clinic. If you’re having the PRP injected more deeply or mixed with hyaluronic acid, you may get some areas of swelling, but these usually disappear in a day.

If you’re having PRP for hair, you’ll be asked to come in 30-60 minutes prior to your appointment time for a topical anaesthesia. After treatment, you’ll be asked not to wash your hair until the next day. Your hair will be oily, so you may wish to bring a hat with you.

PRP with microneedling
If you’re having PRP with microneedling, please come in one hour before your appointment time so that a topical anaesthetic can be applied to the area.

If you’re having an area of your body treated, please wear loose-fitting clothing, as the topical anaesthetic can transfer onto the fabric and cause staining.

How can PRP be administered?

Usually either by mesotherapy, which is lots of tiny superficial injections all over the skin. We commonly employ a cannula when treating an area such as the under-eye or nose-to-mouth lines with concentrated PRP, with a needle inserted deep to the bone. Alternatively, we use a Dermapen (the so-called vampire facial). The method suggested will depend on the exact reason for using PRP, and will be discussed with you at your appointment. For example, if you have scarring, it’s better to use a Dermapen. If you’re treating the skin and mixing PRP with dermal fillers, then a needle is better. For the under-eyes, we prefer a cannula. For a light skin improvement, a mesotherapy gun is used.

How should I prepare for the procedure?

It’s helpful if you don’t wear any makeup when you come in for the procedure, but don’t worry, we can take it off for you. If you’re prone to bruising, you may want to use some arnica or bromelain. If you have an important event coming up, you should schedule your treatment accordingly, remembering that PRP takes a few weeks before you get to see the best results.

How can I avoid bruising?

If you’re prone to bruising, you may wish to use arnica or bromelain

Do I need a check-up?

PRP does not require a check-up after the procedure. However, we’re always here should you have any questions or concerns.

Does it hurt?

Not much at all. The blood is taken in a similar fashion to having a blood test, so it doesn’t hurt any more than this. If the scalp is being injected, you’ll have a local anaesthetic injection or topical anaesthetic prior to treatment. For mesotherapy, no anaesthesia is required.

Will my face go numb?

You won’t have any loss of sensation after this treatment, unless lignocaine is used.

Can I put makeup on afterwards?

If you’re having PRP mesotherapy, it’s advisable not to wear makeup or wash your face until the following day. If your PRP has been injected more deeply, you may wash your face, but try to avoid wearing makeup unless it’s post-surgical makeup.

When does it start to work?

PRP normally takes a few weeks for the effects to become visible. For some people, only one session is required to see good results. However, it’s more common to have between three and five treatment sessions.

Can I go to work afterwards?

Yes, you can return to work after treatment, but in the case of eye rejuvenation, you’re often quite swollen here afterwards. If you’ve had mesotherapy, it’s advisable not to put makeup on afterwards, so it might be better to have the treatment when you have no immediate commitments.

Can I do this treatment whilst pregnant or breastfeeding?

This is not recommended for use during pregnancy or whilst breastfeeding.

How long does it last?

There have been no studies performed on this. As a general rule of thumb, once your initial three to five sessions have been performed, you should aim to have one treatment every three to six months to maintain results.

What happens if I never have PRP again?

Nothing, you’ll simply enjoy the benefits of the PRP for that time and then revert to your pre-treatment state.

How old should I be?

This depends on the rate of facial ageing. Some people develop fine lines and wrinkles early in life, and if the lines are beginning to become ingrained into the tissue then it’s appropriate to commence treatment. Ideally though, we prefer not to treat anyone under 25 without an exceptionally good reason. PRP tends to work better on those who are slightly younger; older patients can still enjoy the benefits, but they may need more sessions for comparable results.

Will I look natural?

Absolutely, yes – because there are no foreign substances being placed in the body. This is your own blood, nothing added – and we’re relying on your body’s natural regenerative process to achieve an improvement.

Will people be able to tell?

As long as your expectations are to keep the results on the natural side, then a person would require an eagle eye to detect any change.

Will I still be able to move?

Yes, PRP does not inhibit muscle movement at all.

What can go wrong?

Complications with PRP are very rare, but as with any injection there is a small risk of bruising.

What does activation mean?

Activation means that growth factors are released upon the PRP coming into contact with coagulation triggers. Some people use an activator such as 10% calcium chloride or bovine collagen. Activation can be caused by trauma from the needle or when the PRP comes into contact with type 1 collagen. PRP activated with thrombin activates very quickly; PRP activated with calcium chloride activates slowly, and with no activation (relying on collagen) it activates incompletely.

What is the difference between PRP and stem cells?

PRP is taken from the blood, whereas stem cells are taken from the fat or bone marrow. PRP is made of growth factors and cytokines that help your body to heal via its existing healing mechanism. PRP is ideal for helping injured or damaged areas that need a jumpstart to begin healing. Stem cells are cells which can be converted into any tissues the body needs, and can regenerate damaged tissues. So, steam cells are like planting new seeds; PRP is like watering the garden.

Some people say PRP doesn’t work. Is this true?

Whilst it is important to be realistic about the results of PRP, just like every aesthetic treatment, it’s not a magic bullet. Here are a few things that PRP is good for:

  • It is effective at inducing skin fibroblasts and fat derived stem cells
  • It acts as a scaffold for injectables such as hyaluronic acid
  • It reduces scars in acne
  • It builds collagen – thicker collagen has been demonstrated in those who have had PRP injections; it has been shown to increase the expression of type 1 collagen in humans
  • It improves skin colour and texture
  • It reduces wrinkle depth
  • It increases skin elasticity
  • It increases skin hydration by augmenting the skin’s own hyaluronic acid content.

Should I go for stem cells or PRP?

PRP is more appropriate than stem cells if a mesotherapy technique is being used, for tightening the skin of the eyelids. If the cost of stem cells is prohibitive, PRP is sufficient for most people.

Can I have PRP instead of wrinkle relaxation or fillers?

Yes, but PRP does not work in the same way, so the results won’t be the same. The outcome of PRP is generally much subtler, so PRP is generally best used in areas not amenable to other injectables, such as the under eye region, or for those who wish to have skin improvement and don’t want moisturiser injections. Of course, you can always combine PRP with hyaluronic acid dermal fillers if you wish to ‘supercharge’ your skin rejuvenation.

Is there any guarantee of results?

PRP is an unpredictable treatment, as almost all of the outcome is dependent on the response of the body to the PRP and the concentration of growth factors contained in the mixture.

Anything else I need to know?

Please note that you are paying for the treatment only and no guarantee is made of any outcome. Refunds cannot be given under any circumstances, as the product has been used and the service has been delivered.


TLC The Lovely Clinic, Chelsea DR Sarah Tonks