What Are Nucleofill Polynucleotides?

Everything You Need To Know About Nucleofill

Nucleofill is our new favourite companion treatment. The injectable uses a polynucleotide-based gel to repair and protect the skin. When used ahead of other treatments, its wound-healing properties magnify anti-ageing and rejuvenating effects. Let’s start by exploring the role of polynucleotides within the body. 


What Are Polynucleotides?

Polynucleotides are like tiny building blocks found in your body. They’re made up of different parts, including a phosphate group, a sugar and a base. You can think of them as Lego pieces that join together to form longer structures called nucleic acids, such as DNA and RNA. They provide instructions, fix any damage and keep your skin cells functioning properly. As you age, changes in these instructions can contribute to visible signs of ageing, such as wrinkles and sagging skin. Nucleofill is a cutting-edge injectable that harnesses the power of polynucleotides to keep your skin looking and feeling its best as you age.

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Nucleofill is an Injectable Moisturiser composed of polynucleotides rather than hyaluronic acid. It is designed to rejuvenate the skin by promoting tissue regeneration and stimulating collagen production. When injected, the gel-like substance improves skin texture, elasticity and overall appearance through several mechanisms. 


Repairing Damaged DNA 

Your skin gets exposed to a lot of things that can harm it, like the sun’s rays and free radicals. Polynucleotides help fix damage to your skin’s DNA, almost like little repair crews that mend cracks in a wall.


Controlling Skin Functions 

As you age, changes in gene expression patterns occur, influencing collagen production and antioxidant defences. This leads to changes in your skin, such as wrinkles or age spots. Polynucleotides help maintain your skin’s structure by stimulating fibroblasts and boosting collagen production. You can think of them as instruction manuals for your skin cells.


Keeping Skin Cells Young 

Telomeres found within cells act as little caps on your chromosomes. Polynucleotides help keep telomeres healthy, which is important because as they get worn down over time, your cells can’t divide as well, leading to ageing. Nucleofill promotes cellular turnover and tissue regeneration, leading to smoother, healthier-looking skin.


Making New Proteins

Your skin needs proteins to stay healthy and repair itself. Polynucleotides help make proteins, including collagen and elastin, ensuring that your skin remains strong and supple.


What Does Nucleofill Treat?

The far-reaching effects of polynucleotides make this injectable a premium treatment for a variety of skin complaints. When you book a consultation with one of the team at The Lovely Clinic, they will analyse your skin and create a bespoke treatment plan. We often recommend polynucleotide injections for the following skin concerns:



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Versatile Treatment

Nucleofill comes in three varieties. The soft gel is suitable for use around the delicate eye area, addressing crow’s feet, eye bags and lost volume. Medium gel addresses thinner skin, such as crepey skin on the neck, and the strong formula treats more robust areas of skin, including the treatment of stretch marks. This injectable is effective as a stand-alone treatment but can also enhance the results of Botox®, Dermal Fillers and INTRAcel.


Book A Consultation 

To explore the diverse range of treatments The Lovely Clinic has to offer, visit our website or schedule a consultation with one of the team. We’ll be happy to discuss the most suitable procedures for your unique skin, whether you want to improve your skin health, slow down the onset of ageing, or treat signs of ageing that have already appeared. Call 020 3695 5400, email hello@thelovelyclinic.co.uk or complete our online booking form. Don’t forget to follow us on Facebook and Instagram, and subscribe to our YouTube channel.   

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